This data set includes single-nucleus transcriptomes from 15,928 total nuclei derived from both frozen and neurosurgical human brain specimens, to survey cell type diversity in the human middle temporal gyrus (MTG). Nuclei from 8 human tissue donors ranging in age from 24-66 years were analyzed, revealing 75 transcriptionally distinct cell types: 45 inhibitory neuron types, 24 excitatory neuron types, and 6 non-neuronal types. Note: these data were included in the subsequent “Human Multiple Cortical Areas - SMART-seq” data set
Taxonomy Name: 20190821_Adult_Human_MTG_SMARTseq
Taxonomy Description: Human MTG SMART-Seq Taxonomy
Species: Human
Version: 1.1.0
CCN Number: CCN201908210
AIT Number: 15.3
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Download the taxonomy AIT file
Conserved cell types with divergent features in human versus mouse cortex
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This study used single cell transcriptomics and performed cellular characterization of eight areas in human neocortex to better understand cortical areal specialization.
A taxonomy of the human middle temporal gyrus developed as part of the Seattle Alzheimer's Disease Brain Cell Atlas
This study used single-nucleus RNA sequencing to systematically survey cells across the entire adult human brain.
