This study used single-nucleus RNA sequencing to systematically survey cells across the entire adult human brain. We sampled more than three million nuclei from approximately 100 dissections across the forebrain, midbrain, and hindbrain in three postmortem donors. Our analysis identified 461 clusters and 3313 subclusters organized largely according to developmental origins and revealing high diversity in midbrain and hindbrain neurons. This work provides the most comprehensive census of cells in adult human brain to date.
Taxonomy Name: 202210140_BICCN-Adult_Human_WholeBrain_10X
Taxonomy Description: Whole Human Brain Taxonomy
Species: Human
Version: 1.0.0
CCN Number: CCN202210140
AIT Number: AIT106
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Transcriptomic diversity of cell types across the adult human brain
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Taxonomy of human middle temporal gyrus generated with SMART-seq data in 2019
This study used single cell transcriptomics and performed cellular characterization of eight areas in human neocortex to better understand cortical areal specialization.
A taxonomy of the human middle temporal gyrus developed as part of the Seattle Alzheimer's Disease Brain Cell Atlas
